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    1. Radiation Hormesis Debate
    2. Massachusetts Tuberculosis patients who were fluoroscopied frequently had lower cancer mortality rates than the patients not fluoroscopied
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    mohandoss99
    Jan 8, 2020
      ·  Edited: Feb 16, 2020

    Massachusetts Tuberculosis patients who were fluoroscopied frequently had lower cancer mortality rates than the patients not fluoroscopied

    In this study (Davis et al., 1989), the all cancer mortality rate was reported for TB patients who were exposed to fluoroscopic radiation and those who were not exposed to the radiation.


    Note: SMR = Standardized Mortality Ratio



    Based on the data, for the fluoroscopically exposed patients, males and females combined, the observed cancer deaths were 424 and the expected cancer deaths were 404, resulting in a SMR of 1.05.


    For the unexposed patients, the observed cancer deaths were 620 whereas the expected cancer deaths were 483, resulting in a SMR of 1.28


    Hence the SMR for fluoroscopied patients can be shown to be:

    1.05/1.28 = 0.82 (95% CI: 0.74-0.89)


    Thus, the overall cancer risk is reduced significantly following fluoroscopic irradiation, consistent with radiation hormesis and contradicting the LNT model.


    References

    DAVIS, F. G. et al. Cancer mortality in a radiation-exposed cohort of Massachusetts tuberculosis patients. Cancer Res, v. 49, n. 21, p. 6130-6, Nov 1 1989. https://www.ncbi.nlm.nih.gov/pubmed/2790825

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